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Characterizing the infection-induced transcriptome of Nasonia vitripennis...

Characterizing the infection-induced transcriptome of Nasonia vitripennis reveals a preponderance of taxonomically-restricted immune genes Timothy B. Sackton, John H. Werren, Andrew G. Clark (Submitted...

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A computational model for histone mark propagation reproduces the...

A computational model for histone mark propagation reproduces the distribution of heterochromatin in different human cell types Veit Schwämmle, Ole Nørregaard Jensen (Submitted on 27 Sep 2013)...

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The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation...

The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation Qi Zhou, Christopher E. Ellison, Vera B. Kaiser, Artyom A. Alekseyenko, Andrey A. Gorchakov,...

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Integrating diverse datasets improves developmental enhancer prediction

Integrating diverse datasets improves developmental enhancer prediction Genevieve D. Erwin, Rebecca M. Truty, Dennis Kostka, Katherine S. Pollard, John A. Capra (Submitted on 27 Sep 2013)...

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A latent factor model with a mixture of sparse and dense factors to model...

A latent factor model with a mixture of sparse and dense factors to model gene expression data with confounding effects Chuan Gao, Christopher D Brown, Barbara E Engelhardt (Submitted on 17 Oct 2013)...

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The Functional Consequences of Variation in Transcription Factor Binding

The Functional Consequences of Variation in Transcription Factor Binding Darren A. Cusanovich, Bryan Pavlovic, Jonathan K. Pritchard, Yoav Gilad (Submitted on 18 Oct 2013) One goal of human genetics is...

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Improved annotation of 3-prime untranslated regions and complex loci by...

Improved annotation of 3-prime untranslated regions and complex loci by combination of strand-specific Direct RNA Sequencing, RNA-seq and ESTs Nick Schurch, Christian Cole, Alexander Sherstnev, Junfang...

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Drosophila embryogenesis scales uniformly across temperature and...

Drosophila embryogenesis scales uniformly across temperature and developmentally diverse species Steven Gregory Kuntz, Michael B Eisen Temperature affects both the timing and outcome of animal...

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Joint analysis of functional genomic data and genome-wide association studies...

Joint analysis of functional genomic data and genome-wide association studies of 18 human traits Joseph Pickrell Annotations of gene structures and regulatory elements can inform genome-wide...

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Comment on “TopHat2: accurate alignment of transcriptomes in the presence of...

Comment on “TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions” by Kim et al. Alexander Dobin, Thomas R Gingeras In the recent paper by Kim et al....

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Sex-biased expression of microRNAs in Drosophila melanogaster

Sex-biased expression of microRNAs in Drosophila melanogaster Antonio Marco (Submitted on 11 Dec 2013) Most animals have separate sexes. The differential expression of gene products, in particular that...

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Author post: Sex-biased microRNAs in Drosophila melanogaster

This guest post is by Antonio Marco (@amarcobio) on his paper: Sex-biased microRNAs in Drosophila melanogaster The expression profile of a gene affects its evolutionary fate. Conversely, the...

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Impact of RNA degradation on measurements of gene expression

Impact of RNA degradation on measurements of gene expression Irene Gallego Romero, Athma A. Pai, Jenny Tung, Yoav Gilad The use of low quality RNA samples in whole-genome gene expression profiling...

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motifDiverge: a model for assessing the statistical significance of gene...

motifDiverge: a model for assessing the statistical significance of gene regulatory motif divergence between two DNA sequences Dennis Kostka, Tara Friedrich, Alisha K. Holloway, Katherine S. Pollard...

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A chromatin structure based model accurately predicts DNA replication timing...

A chromatin structure based model accurately predicts DNA replication timing in human cells Yevgeniy Gindin, Manuel S. Valenzuela, Mirit I. Aladjem, Paul S. Meltzer, Sven Bilke Subjects: Subcellular...

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READemption – A tool for the computational analysis of deep-sequencing-based...

READemption – A tool for the computational analysis of deep-sequencing-based transcriptome data Konrad Ulrich Förstner, Jörg Vogel, Cynthia Mira Sharma Summary: RNA-Seq has become a potent and widely...

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Estimating transcription factor abundance and specificity from genome-wide...

Estimating transcription factor abundance and specificity from genome-wide binding profiles Nicolae Radu Zabet, Boris Adryan Comments: 39 pages, 25 figures, 10 tables Subjects: Quantitative Methods...

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Evolution of bow-tie architectures in biology

Evolution of bow-tie architectures in biology Tamar Friedlander, Avraham E. Mayo, Tsvi Tlusty, Uri Alon Subjects: Molecular Networks (q-bio.MN) Bow-tie or hourglass structure is a common architectural...

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When genomes collide: multiple modes of germline misregulation in a dysgenic...

When genomes collide: multiple modes of germline misregulation in a dysgenic syndrome of Drosophila virilis Mauricio A. Galdos, Alexandra A. Erwin, Michelle L. Wickersheim, Chris C. Harrison, Kendra D....

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RNA-seq gene profiling – a systematic empirical comparison

RNA-seq gene profiling – a systematic empirical comparison Nuno A Fonseca, John A Marioni, Alvis Brazma Accurately quantifying gene expression levels is a key goal of experiments using RNA-sequencing...

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